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Dextrose Injection Therapy

Prolotherapy

An age-old approach — strengthening tissue at the source.

What Is Prolotherapy?

Injection of a sterile, concentrated glucose (dextrose) solution into damaged connective tissue. It creates controlled osmotic stress, activating the body's natural healing response and promoting tissue strengthening.

How It Works

The concentrated dextrose solution creates controlled osmotic stress at the injection site. This activates the body's natural inflammatory healing cascade — drawing growth factors, fibroblasts, and repair cells to the area to strengthen weakened or damaged tissue.

Conditions Treated

  • Chronic musculoskeletal pain
  • Sports-related tendinopathies
  • Chronic low back pain
  • Lower limb tendinopathy
  • Knee osteoarthritis

The Prolotherapy Process

01

Injection

A sterile, concentrated dextrose solution is injected directly into the damaged ligament or tendon insertion point.

02

Controlled Response

The hyperosmolar solution creates controlled osmotic stress, activating your body's inflammatory healing cascade.

03

Tissue Strengthening

Fibroblasts are recruited, collagen production increases, and the weakened tissue is strengthened at its attachment point.

Clinical Evidence Highlights

Systematic review confirms dextrose prolotherapy is effective for chronic musculoskeletal pain. [12]

Randomized trial shows significant improvement in lower limb tendinopathy outcomes. [15]

Meta-analysis supports efficacy for knee osteoarthritis pain and function. [17]

Evidence supports use in sports-related tendinopathies and chronic low back pain. [13]

Ready to Try Prolotherapy?

Call to schedule your consultation with Dr. McDougall and find out if prolotherapy is right for your condition.

Book a Consultation — 541-813-1797